(+632) 7110427 | (+632) 7110383
Integrity Aesthetic Building, 788 Banawe Avenue, Quezon City, Philippines
Skin ageing caused by systematic sun exposure, facial blemishes
due to excessive pigmentation and, in general, imperfections caused
by melanin, are more and more common problems today…
“Dark blemishes”, especially on hands and face, are one of the
greatest aesthetic concerns of modern men and women…
It will only be possible to remove the anti-aesthetic skin blemishes
and recover the smoothness of the skin, bringing back its
luminosity, with a treatment that has a direct effect on the intimate
formation process of the pigment (melanin).
Cosmelan® Depigmentation treatment guarantees the improvement
of the anti-aesthetic skin blemishes with a very high safety margin.
Cosmelan® Depigmentation treatment’s principal action is the
elimination of melanin patches on the face (melasma and chloasma).
Cosmelan® Depigmentation treatment involves a very versatile,
dynamic process which is easily adapted to the needs of each
Cosmelan® Depigmentation treatment action mechanism is based
on the inhibition of tyrosinase, a basic enzyme in the melanin
formation process. Several of the substances present in the
Cosmelan® formula act by blocking this enzyme, or even by
inverting the metabolic process of the transformation chain.
Melanogenesis comprises the following stages:
TYROSINE proceeds to DOPA by means of TYROSINASE.
DOPA proceeds to DOPAQUINONE by means of TYROSINASE.
DOPAQUINONE proceeds to PHAEOMELANINE and EUMELANIN
by means of oxidation and cyclization.
Cosmelan works by blocking the process that causes
hyperpigmentation. It works for:
• Brown Spots
• Blotchy Skin
• Post-inflammatory hyperpigmentation
• Prevention of hyperpigmentation post-laser and post-peel
ACTIVE INGREDIENTS - Cosmelan® Pack
Cosmelan® 1 – Cream (10g)
Azelaic Acid, Kojic Acid, Phytic Acid, Ascorbic Acid, Arbutine,
Cosmelan® 2 – Maintenance Cream (30g)
Titanium Dioxide, Kojic Acid, Phytic Acid, Ascorbic Acid
mesoestetic® Hydra Vital Factor K Cream (50ml)
Hydro nutritional cream for face and neck. Hydroviton, VItamin K,
Vitamin E, Amniotic fluid, Glycerine, Silicone oil.